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Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application

As a DNA receptor in the cytoplasm, cyclic GMP-AMP synthase (cGAS) contributes to the recognition of abnormal DNA in the cytoplasm and contributes to the stimulator of interferon genes (STING) signaling pathway. cGAS could mediate the expression of interferon-related genes, inflammatory-related fact...

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Библиографические подробности
Опубликовано в: :Onco Targets Ther
Главные авторы: Pu, Feifei, Chen, Fengxia, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
Формат: Artigo
Язык:Inglês
Опубликовано: Dove 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935450/
https://ncbi.nlm.nih.gov/pubmed/33688199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S298958
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