Echinatin effectively protects against NLRP3 inflammasome–driven diseases by targeting HSP90

Aberrant activation of NLRP3 inflammasome has been implicated in a variety of human inflammatory diseases, but currently, no pharmacological NLRP3 inhibitor has been approved. In this study, we showed that echinatin, the ingredient of the traditional herbal medicine licorice, effectively suppresses...

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Detalles Bibliográficos
Publicado en:JCI Insight
Main Authors: Xu, Guang, Fu, Shubin, Zhan, Xiaoyan, Wang, Zhilei, Zhang, Ping, Shi, Wei, Qin, Nan, Chen, Yuanyuan, Wang, Chunyu, Niu, Ming, Guo, Yuming, Wang, Jiabo, Bai, Zhaofang, Xiao, Xiaohe
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934863/
https://ncbi.nlm.nih.gov/pubmed/33350984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134601
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