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TGFB1/INHBA Homodimer/Nodal-SMAD2/3 Signaling Network: A Pivotal Molecular Target in PDAC Treatment

Pancreatic cancer remains a grueling disease that is projected to become the second-deadliest cancer in the next decade. Standard treatment of pancreatic cancer is chemotherapy, which mainly targets the differentiated population of tumor cells; however, it paradoxically sets the roots of tumor relap...

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Pubblicato in:Mol Ther
Autori principali: Abdel Mouti, Mai, Pauklin, Siim
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934636/
https://ncbi.nlm.nih.gov/pubmed/33429081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.01.002
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