The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC

Treating pancreatic ductal adenocarcinoma (PDAC) remains a major hurdle in the field of oncology. Less than half of patients respond to frontline chemotherapy and the pancreatic tumor microenvironment limits the efficacy of immunotherapeutic approaches. Targeted therapies could serve as effective tr...

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Veröffentlicht in:PLoS One
Hauptverfasser: Brown, Matthew, Zhang, Wanbin, Yan, Deyue, Kenath, Rajath, Le, Le, Wang, He, Delitto, Daniel, Ostrov, David, Robertson, Keith, Liu, Chen, Pham, Kien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957139/
https://ncbi.nlm.nih.gov/pubmed/31929540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226917
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