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The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC

Treating pancreatic ductal adenocarcinoma (PDAC) remains a major hurdle in the field of oncology. Less than half of patients respond to frontline chemotherapy and the pancreatic tumor microenvironment limits the efficacy of immunotherapeutic approaches. Targeted therapies could serve as effective tr...

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Bibliographic Details
Published in:PLoS One
Main Authors: Brown, Matthew, Zhang, Wanbin, Yan, Deyue, Kenath, Rajath, Le, Le, Wang, He, Delitto, Daniel, Ostrov, David, Robertson, Keith, Liu, Chen, Pham, Kien
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957139/
https://ncbi.nlm.nih.gov/pubmed/31929540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226917
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