SIRT 1 Overexpression is Associated with Metastasis of Pancreatic Ductal Adenocarcinoma (PDAC) and Promotes Migration and Growth of PDAC Cells

BACKGROUND: SIRT 1, as a class III histone deacetylase (HDAC), is implicated in the initiation and progression of malignancies. However, the association of SIRT 1 with tumorigenesis or progression of pancreatic ductal adenocarcinoma (PDAC) is not clear. MATERIAL/METHODS: In our study we investigated...

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Udgivet i:Med Sci Monit
Main Authors: Li, Siqin, Hong, Hua, Lv, Huicheng, Wu, Guozhu, Wang, Zhigang
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2016
Fag:
Lab/In Vitro Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917327/
https://ncbi.nlm.nih.gov/pubmed/27170223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.896697
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