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Extraction of mRNA from stalled ribosomes by the Ski complex

The evolutionarily conserved Ski2-Ski3-Ski8 (Ski) complex containing the 3′→5′ RNA helicase Ski2 binds to 80S ribosomes near the mRNA entrance and facilitates 3′→5′ exosomal degradation of mRNA during ribosome-associated mRNA surveillance pathways. Here, we assayed Ski’s activity using an in vitro r...

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Publicat a:Mol Cell
Autors principals: Zinoviev, Alexandra, Ayupov, Rustam K., Abaeva, Irina S., Hellen, Christopher U. T., Pestova, Tatyana V.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934606/
https://ncbi.nlm.nih.gov/pubmed/32006463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.01.011
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