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Extraction of mRNA from stalled ribosomes by the Ski complex
The evolutionarily conserved Ski2-Ski3-Ski8 (Ski) complex containing the 3′→5′ RNA helicase Ski2 binds to 80S ribosomes near the mRNA entrance and facilitates 3′→5′ exosomal degradation of mRNA during ribosome-associated mRNA surveillance pathways. Here, we assayed Ski’s activity using an in vitro r...
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| Publicado en: | Mol Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7934606/ https://ncbi.nlm.nih.gov/pubmed/32006463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.01.011 |
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