Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

BACKGROUND: Linezolid is administered as a fixed dose to all patients despite evidence of overexposure and thrombocytopenia in renal impairment. The aims of this study were to evaluate the risk of thrombocytopenia and the utility of therapeutic drug monitoring (TDM), and to propose alternate dosing...

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Dades bibliogràfiques
Publicat a:BMC Pharmacol Toxicol
Autors principals: Kawasuji, Hitoshi, Tsuji, Yasuhiro, Ogami, Chika, Kimoto, Kou, Ueno, Akitoshi, Miyajima, Yuki, Kawago, Koyomi, Sakamaki, Ippei, Yamamoto, Yoshihiro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934392/
https://ncbi.nlm.nih.gov/pubmed/33663616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-021-00479-w
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