Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

BACKGROUND: Linezolid is administered as a fixed dose to all patients despite evidence of overexposure and thrombocytopenia in renal impairment. The aims of this study were to evaluate the risk of thrombocytopenia and the utility of therapeutic drug monitoring (TDM), and to propose alternate dosing...

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Bibliografiske detaljer
Udgivet i:BMC Pharmacol Toxicol
Main Authors: Kawasuji, Hitoshi, Tsuji, Yasuhiro, Ogami, Chika, Kimoto, Kou, Ueno, Akitoshi, Miyajima, Yuki, Kawago, Koyomi, Sakamaki, Ippei, Yamamoto, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934392/
https://ncbi.nlm.nih.gov/pubmed/33663616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-021-00479-w
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