Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

BACKGROUND: Linezolid is administered as a fixed dose to all patients despite evidence of overexposure and thrombocytopenia in renal impairment. The aims of this study were to evaluate the risk of thrombocytopenia and the utility of therapeutic drug monitoring (TDM), and to propose alternate dosing...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Kawasuji, Hitoshi, Tsuji, Yasuhiro, Ogami, Chika, Kimoto, Kou, Ueno, Akitoshi, Miyajima, Yuki, Kawago, Koyomi, Sakamaki, Ippei, Yamamoto, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934392/
https://ncbi.nlm.nih.gov/pubmed/33663616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-021-00479-w
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