The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents

MGMT-promoter methylation is associated with favorable outcome in glioblastoma. The aim of this study was to determine whether the absolute number of methylated Cytosine-Guanine-dinucleotide-(CpG-)sites within the DMR-2 island of the MGMT-promoter may correlate with outcome in a qualitative or quant...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol Commun
Egile Nagusiak: Siller, Sebastian, Lauseker, Michael, Karschnia, Philipp, Niyazi, Maximilian, Eigenbrod, Sabina, Giese, Armin, Tonn, Joerg-Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934240/
https://ncbi.nlm.nih.gov/pubmed/33663593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01134-5
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