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P14.02 Influence of individual CpG methylation status on outcome in adult patients with glioblastoma multiforme receiving alkylating agent treatment

Background: Methylation of the O-6-methylguanine-DNA methyltransferase (MGMT) promotor causes gene silencing and has been associated with a favourable prognosis in patients with glioblastoma multiforme (GBM) receiving alkylating chemotherapy. However, analysis of MGMT promotor methylation is usually...

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Publicado en:Neuro Oncol
Main Authors: Siller, S, Lauseker, M, Giese, A, Tonn, J, Niyazi, K, Thon, N, Suchorska, B, Kreth, F
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795930/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.238
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