ORMDL3 Functions as a Negative Regulator of Antigen-Mediated Mast Cell Activation via an ATF6-UPR-Autophagy–Dependent Pathway

Antigen (Ag)-mediated mast cell activation plays a critical role in the immunopathology of IgE-dependent allergic diseases. Restraining the signaling cascade that regulates the release of mast cell-derived inflammatory mediators is an attractive therapeutic strategy to treat allergic diseases. Oroso...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Li, Jia, Ullah, Md Ashik, Jin, Hongping, Liang, Yuting, Lin, Lihui, Wang, Juan, Peng, Xia, Liao, Huanjin, Li, Yanning, Ge, Yiqin, Li, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933793/
https://ncbi.nlm.nih.gov/pubmed/33679742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.604974
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