ORMDL2 Deficiency Potentiates the ORMDL3-Dependent Changes in Mast Cell Signaling

The systemic anaphylactic reaction is a life-threatening allergic response initiated by activated mast cells. Sphingolipids are an essential player in the development and attenuation of this response. De novo synthesis of sphingolipids in mammalian cells is inhibited by the family of three ORMDL pro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bugajev, Viktor, Halova, Ivana, Demkova, Livia, Cernohouzova, Sara, Vavrova, Petra, Mrkacek, Michal, Utekal, Pavol, Draberova, Lubica, Kuchar, Ladislav, Schuster, Björn, Draber, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905224/
https://ncbi.nlm.nih.gov/pubmed/33643282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591975
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