ORMDL2 Deficiency Potentiates the ORMDL3-Dependent Changes in Mast Cell Signaling

The systemic anaphylactic reaction is a life-threatening allergic response initiated by activated mast cells. Sphingolipids are an essential player in the development and attenuation of this response. De novo synthesis of sphingolipids in mammalian cells is inhibited by the family of three ORMDL pro...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Bugajev, Viktor, Halova, Ivana, Demkova, Livia, Cernohouzova, Sara, Vavrova, Petra, Mrkacek, Michal, Utekal, Pavol, Draberova, Lubica, Kuchar, Ladislav, Schuster, Björn, Draber, Petr
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905224/
https://ncbi.nlm.nih.gov/pubmed/33643282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591975
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