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Screening for new peptide substrates for the development of albumin binding anticancer pro-drugs that are cleaved by prostate-specific antigen (PSA) to improve the anti tumor efficacy

Several attempts have been made over the past decade to explore the concept of prodrug strategies that exploit PSA as a molecular target for the release of anticancer drugs in prostate tumors using various prostate specific antigen (PSA)-cleavable peptide linkers, but the desired antitumor and antim...

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Veröffentlicht in:Biochem Biophys Rep
Hauptverfasser: Elsadek, Bakheet E.M., Hassan, Mohammed H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933701/
https://ncbi.nlm.nih.gov/pubmed/33718631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2021.100966
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