Proteolytic Activity of Prostate-Specific Antigen (PSA) towards Protein Substrates and Effect of Peptides Stimulating PSA Activity

Prostate-specific antigen (PSA or kallikrein-related peptidase-3, KLK3) exerts chymotrypsin-like proteolytic activity. The main biological function of PSA is the liquefaction of the clot formed after ejaculation by cleavage of semenogelins I and II in seminal fluid. PSA also cleaves several other su...

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Bibliografiske detaljer
Main Authors: Mattsson, Johanna M., Ravela, Suvi, Hekim, Can, Jonsson, Magnus, Malm, Johan, Närvänen, Ale, Stenman, Ulf-Håkan, Koistinen, Hannu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169579/
https://ncbi.nlm.nih.gov/pubmed/25237904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107819
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