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Cellular Metabolites Regulate Central Nucleic Acid Sensing Pathways
Detection of pathogen-derived DNA or RNA species by cellular nucleic acid sensors prompts release of anti-microbial interferons and cytokines. In contrast to their protective anti-microbial functions, inappropriate or excessive activation of nucleic acid sensors can cause inflammatory diseases. Nucl...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7933466/ https://ncbi.nlm.nih.gov/pubmed/33679790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.635738 |
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