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Cellular Metabolites Regulate Central Nucleic Acid Sensing Pathways

Detection of pathogen-derived DNA or RNA species by cellular nucleic acid sensors prompts release of anti-microbial interferons and cytokines. In contrast to their protective anti-microbial functions, inappropriate or excessive activation of nucleic acid sensors can cause inflammatory diseases. Nucl...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Blay-Cadanet, Julia, Pedersen, Alice, Holm, Christian Kanstrup
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933466/
https://ncbi.nlm.nih.gov/pubmed/33679790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.635738
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