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Sphingosine 1-phosphate Receptor Modulator Therapy for Multiple Sclerosis: Differential Downstream Receptor Signalling and Clinical Profile Effects

Lysophospholipids are a class of bioactive lipid molecules that produce their effects through various G protein-coupled receptors (GPCRs). Sphingosine 1-phosphate (S1P) is perhaps the most studied lysophospholipid and has a role in a wide range of physiological and pathophysiological events, via sig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drugs
Hauptverfasser: Chun, Jerold, Giovannoni, Gavin, Hunter, Samuel F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932974/
https://ncbi.nlm.nih.gov/pubmed/33289881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-020-01431-8
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