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Sphingosine 1-phosphate Receptor Modulator Therapy for Multiple Sclerosis: Differential Downstream Receptor Signalling and Clinical Profile Effects

Lysophospholipids are a class of bioactive lipid molecules that produce their effects through various G protein-coupled receptors (GPCRs). Sphingosine 1-phosphate (S1P) is perhaps the most studied lysophospholipid and has a role in a wide range of physiological and pathophysiological events, via sig...

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Detalhes bibliográficos
Publicado no:Drugs
Main Authors: Chun, Jerold, Giovannoni, Gavin, Hunter, Samuel F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932974/
https://ncbi.nlm.nih.gov/pubmed/33289881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-020-01431-8
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