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A mathematical model of the role of aggregation in sonic hedgehog signalling
Effective regulation of the sonic hedgehog (Shh) signalling pathway is essential for normal development in a wide variety of species. Correct Shh signalling requires the formation of Shh aggregates on the surface of producing cells. Shh aggregates subsequently diffuse away and are recognised in rece...
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| 發表在: | PLoS Comput Biol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7932509/ https://ncbi.nlm.nih.gov/pubmed/33617524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008562 |
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