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A mathematical model of the role of aggregation in sonic hedgehog signalling
Effective regulation of the sonic hedgehog (Shh) signalling pathway is essential for normal development in a wide variety of species. Correct Shh signalling requires the formation of Shh aggregates on the surface of producing cells. Shh aggregates subsequently diffuse away and are recognised in rece...
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7932509/ https://ncbi.nlm.nih.gov/pubmed/33617524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008562 |
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