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Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease

The inflammatory hypothesis posits that sustained neuroinflammation is sufficient to induce neurodegeneration and the development of Alzheimer’s disease (AD) and Alzheimer’s dementia. One potential source of inflammation is the intestine which harbors pro-inflammatory microorganisms capable of promo...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Voigt, Robin M., Raeisi, Shohreh, Yang, Jingyun, Leurgans, Sue, Forsyth, Christopher B., Buchman, Aron S., Bennett, David A., Keshavarzian, Ali
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932071/
https://ncbi.nlm.nih.gov/pubmed/33661922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240342
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