Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease

The inflammatory hypothesis posits that sustained neuroinflammation is sufficient to induce neurodegeneration and the development of Alzheimer’s disease (AD) and Alzheimer’s dementia. One potential source of inflammation is the intestine which harbors pro-inflammatory microorganisms capable of promo...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Voigt, Robin M., Raeisi, Shohreh, Yang, Jingyun, Leurgans, Sue, Forsyth, Christopher B., Buchman, Aron S., Bennett, David A., Keshavarzian, Ali
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932071/
https://ncbi.nlm.nih.gov/pubmed/33661922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240342
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