Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease

The inflammatory hypothesis posits that sustained neuroinflammation is sufficient to induce neurodegeneration and the development of Alzheimer’s disease (AD) and Alzheimer’s dementia. One potential source of inflammation is the intestine which harbors pro-inflammatory microorganisms capable of promo...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Voigt, Robin M., Raeisi, Shohreh, Yang, Jingyun, Leurgans, Sue, Forsyth, Christopher B., Buchman, Aron S., Bennett, David A., Keshavarzian, Ali
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932071/
https://ncbi.nlm.nih.gov/pubmed/33661922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240342
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