Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease

The inflammatory hypothesis posits that sustained neuroinflammation is sufficient to induce neurodegeneration and the development of Alzheimer’s disease (AD) and Alzheimer’s dementia. One potential source of inflammation is the intestine which harbors pro-inflammatory microorganisms capable of promo...

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Vydáno v:PLoS One
Hlavní autoři: Voigt, Robin M., Raeisi, Shohreh, Yang, Jingyun, Leurgans, Sue, Forsyth, Christopher B., Buchman, Aron S., Bennett, David A., Keshavarzian, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932071/
https://ncbi.nlm.nih.gov/pubmed/33661922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240342
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