Presence of PTPN2 SNP rs1893217 Enhances the Anti-inflammatory Effect of Spermidine

BACKGROUND: The single nucleotide polymorphism (SNP) rs1893217 within the gene locus encoding PTPN2 represents a risk factor for inflammatory bowel disease (IBD). Our previous work demonstrated reduced PTPN2 activity and subsequently increased inflammatory signaling upon presence of SNP rs1893217. T...

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Bibliografiske detaljer
Udgivet i:Inflamm Bowel Dis
Main Authors: Niechcial, Anna, Butter, Matthias, Manz, Salomon, Obialo, Nicole, Bäbler, Katharina, van der Lely, Lisa, Lang, Silvia, Gottier, Claudia, McCole, Declan F, Scharl, Michael, Spalinger, Marianne R
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Basic Science Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931847/
https://ncbi.nlm.nih.gov/pubmed/32031616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izaa013
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