PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function.

BACKGROUND & AIMS: The mechanisms by which macrophages regulate intestinal epithelial cell (IEC) barrier properties are poorly understood. Protein tyrosine phosphatase non-receptor type 2 (PTPN2) protects the IEC barrier from inflammation-induced disruption and regulates macrophage functions. We...

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Publicado en:Gastroenterology
Autores principales: Spalinger, Marianne R., Sayoc-Becerra, Anica, Santos, Alina N., Shawki, Ali, Canale, Vinicius, Krishnan, Moorthy, Niechcial, Anna, Obialo, Nicole, Scharl, Michael, Li, Jiang, Nair, Meera G., McCole, Declan F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680443/
https://ncbi.nlm.nih.gov/pubmed/32652144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.07.004
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