GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo

BACKGROUND: Insulin secretion from the pancreatic β-cell is finely modulated by different signals to allow an adequate control of glucose homeostasis. Incretin hormones such as glucagon-like peptide-1 (GLP-1) act as key physiological potentiators of insulin release through binding to the G protein-c...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Arcones, Alba C., Vila-Bedmar, Rocío, Mirasierra, Mercedes, Cruces-Sande, Marta, Vallejo, Mario, Jones, Ben, Tomas, Alejandra, Mayor, Federico, Murga, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931601/
https://ncbi.nlm.nih.gov/pubmed/33658023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-00966-w
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