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Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2

Insulin resistance is a common feature of obesity and predisposes individuals to various prevalent pathological conditions. G protein-coupled receptor kinase 2 (GRK2) integrates several signal transduction pathways and is emerging as a physiologically relevant inhibitor of insulin signaling. GRK2 ab...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Vila-Bedmar, Rocio, Cruces-Sande, Marta, Lucas, Elisa, Willemen, Hanneke L.D.M., Heijnen, Cobi J., Kavelaars, Annemieke, Mayor, Federico, Murga, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586018/
https://ncbi.nlm.nih.gov/pubmed/26198359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa4374
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