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Navigating the Unnatural Reaction Space: Directed Evolution of Heme Proteins for Selective Carbene and Nitrene Transfer

[Image: see text] Despite the astonishing diversity of naturally occurring biocatalytic processes, enzymes do not catalyze many of the transformations favored by synthetic chemists. Either nature does not care about the specific products, or if she does, she has adopted a different synthetic strateg...

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Bibliografische gegevens
Gepubliceerd in:Acc Chem Res
Hoofdauteurs: Yang, Yang, Arnold, Frances H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2021
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931446/
https://ncbi.nlm.nih.gov/pubmed/33491448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00591
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