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Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design

Identification of viral immune escape mutations that compromise HIV’s ability to replicate may aid rational attenuation-based vaccine design. Previously we reported amino acids associated with altered viral replication capacity (RC) from a sequence-function analysis of 487 patient-derived RT-integra...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Ojwach, Doty B.A., Madlala, Paradise, Gordon, Michelle, Ndung’u, Thumbi, Mann, Jaclyn K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931244/
https://ncbi.nlm.nih.gov/pubmed/33316731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2020.12.003
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