Cyclophilin D‐dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia

Microorganisms or LPS (lipopolysaccharide), an outer membrane component of Gram‐negative bacteria, can induce a systemic inflammatory response that leads to sepsis, multiple organ dysfunction, and mortality. Here, we investigated the role of cyclophilin D (CypD)‐dependent mitochondrial permeability...

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Dettagli Bibliografici
Pubblicato in:FEBS Open Bio
Autori principali: Veres, Balazs, Eros, Krisztian, Antus, Csenge, Kalman, Nikoletta, Fonai, Fruzsina, Jakus, Peter Balazs, Boros, Eva, Hegedus, Zoltan, Nagy, Istvan, Tretter, Laszlo, Gallyas, Ferenc, Sumegi, Balazs
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931201/
https://ncbi.nlm.nih.gov/pubmed/33471430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13091
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