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TET Enzymes and 5-Hydroxymethylcytosine in Neural Progenitor Cell Biology and Neurodevelopment

Studies of tissue-specific epigenomes have revealed 5-hydroxymethylcytosine (5hmC) to be a highly enriched and dynamic DNA modification in the metazoan nervous system, inspiring interest in the function of this epigenetic mark in neurodevelopment and brain function. 5hmC is generated by oxidation of...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: MacArthur, Ian C., Dawlaty, Meelad M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930563/
https://ncbi.nlm.nih.gov/pubmed/33681230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.645335
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