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TET Enzymes and 5-Hydroxymethylcytosine in Neural Progenitor Cell Biology and Neurodevelopment

Studies of tissue-specific epigenomes have revealed 5-hydroxymethylcytosine (5hmC) to be a highly enriched and dynamic DNA modification in the metazoan nervous system, inspiring interest in the function of this epigenetic mark in neurodevelopment and brain function. 5hmC is generated by oxidation of...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: MacArthur, Ian C., Dawlaty, Meelad M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930563/
https://ncbi.nlm.nih.gov/pubmed/33681230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.645335
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