A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy

In the mammalian hippocampus, adult-born granule cells (abGCs) contribute to the function of the dentate gyrus (DG). Disruption of the DG circuitry causes spontaneous recurrent seizures (SRS), which can lead to epilepsy. Although abGCs contribute to local inhibitory feedback circuitry, whether they...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lybrand, Zane R., Goswami, Sonal, Zhu, Jingfei, Jarzabek, Veronica, Merlock, Nikolas, Aktar, Mahafuza, Smith, Courtney, Zhang, Ling, Varma, Parul, Cho, Kyung-Ok, Ge, Shaoyu, Hsieh, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930276/
https://ncbi.nlm.nih.gov/pubmed/33658509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21649-8
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