A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy

In the mammalian hippocampus, adult-born granule cells (abGCs) contribute to the function of the dentate gyrus (DG). Disruption of the DG circuitry causes spontaneous recurrent seizures (SRS), which can lead to epilepsy. Although abGCs contribute to local inhibitory feedback circuitry, whether they...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Lybrand, Zane R., Goswami, Sonal, Zhu, Jingfei, Jarzabek, Veronica, Merlock, Nikolas, Aktar, Mahafuza, Smith, Courtney, Zhang, Ling, Varma, Parul, Cho, Kyung-Ok, Ge, Shaoyu, Hsieh, Jenny
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930276/
https://ncbi.nlm.nih.gov/pubmed/33658509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21649-8
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