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Mice with conditional NeuroD1 knockout display reduced aberrant hippocampal neurogenesis but no change in epileptic seizures

Adult neurogenesis is significantly increased in the hippocampus of rodent models of temporal lobe epilepsy (TLE). These adult-generated neurons have recently been shown to play a contributing role in the development of spontaneous recurrent seizures (SRS). In order to eventually target pro-epilepti...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Brulet, Rebecca, Zhu, Jingfei, Aktar, Mahafuza, Hsieh, Jenny, Cho, Kyung-Ok
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503142/
https://ncbi.nlm.nih.gov/pubmed/28427858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.04.005
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