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Phosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells
Multiple myeloma (MM), a treatable but incurable malignancy, is characterized by the growth of clonal plasma cells in protective niches in the bone marrow. MM cells depend on expression of BCL-2 family proteins, in particular MCL-1, for survival. The regulation of MCL-1 is complex and cell type-depe...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7930201/ https://ncbi.nlm.nih.gov/pubmed/33658484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03351-7 |
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