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Immunogenicity of prime-boost protein subunit vaccine strategies against SARS-CoV-2 in mice and macaques
SARS-CoV-2 vaccines are advancing into human clinical trials, with emphasis on eliciting high titres of neutralising antibodies against the viral spike (S). However, the merits of broadly targeting S versus focusing antibody onto the smaller receptor binding domain (RBD) are unclear. Here we assess...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7930087/ https://ncbi.nlm.nih.gov/pubmed/33658497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21665-8 |
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