Immunogenicity of prime-boost protein subunit vaccine strategies against SARS-CoV-2 in mice and macaques

SARS-CoV-2 vaccines are advancing into human clinical trials, with emphasis on eliciting high titres of neutralising antibodies against the viral spike (S). However, the merits of broadly targeting S versus focusing antibody onto the smaller receptor binding domain (RBD) are unclear. Here we assess...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tan, Hyon-Xhi, Juno, Jennifer A., Lee, Wen Shi, Barber-Axthelm, Isaac, Kelly, Hannah G., Wragg, Kathleen M., Esterbauer, Robyn, Amarasena, Thakshila, Mordant, Francesca L., Subbarao, Kanta, Kent, Stephen J., Wheatley, Adam K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930087/
https://ncbi.nlm.nih.gov/pubmed/33658497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21665-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados