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Dopamine activates NF-κB and primes the NLRP3 inflammasome in primary human macrophages

Induction of innate immune genes in the brain is thought to be a major factor in the development of addiction to substances of abuse. As the major component of the innate immune system in the brain, aberrant activation of myeloid cells such as macrophages and microglia due to substance use may media...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Behav Immun Health
Prif Awduron: Nolan, R.A., Reeb, K.L., Rong, Y., Matt, S.M., Johnson, H.S., Runner, K., Gaskill, P.J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7929492/
https://ncbi.nlm.nih.gov/pubmed/33665636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbih.2019.100030
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