Controversies around the function of LARP1

The RNA-binding protein LARP1 has generated interest in recent years for its role in the mTOR signalling cascade and its regulation of terminal oligopyrimidine (TOP) mRNA translation. Paradoxically, some scientists have shown that LARP1 represses TOP translation while others that LARP1 activates it....

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Bibliographic Details
Published in:RNA Biol
Main Authors: Berman, Andrea J., Thoreen, Carson C., Dedeic, Zinaida, Chettle, James, Roux, Philippe P., Blagden, Sarah P.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928164/
https://ncbi.nlm.nih.gov/pubmed/32233986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1733787
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