Optimization of an Assay To Determine Colonization Resistance to Clostridioides difficile in Fecal Samples from Healthy Subjects and Those Treated with Antibiotics

A healthy, intact gut microbiota is often resistant to colonization by gastrointestinal pathogens. During periods of dysbiosis, however, organisms such as Clostridioides difficile can thrive. We describe an optimized in vitro colonization resistance assay for C. difficile in stool (CRACS) and demons...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Harris, Hannah C., Best, Emma L., Normington, Charmaine, Saint-Lu, Nathalie, Sablier-Gallis, Frédérique, de Gunzburg, Jean, Andremont, Antoine, Wilcox, Mark H., Chilton, Caroline H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927831/
https://ncbi.nlm.nih.gov/pubmed/33139292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01401-20
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