Antibiotic-Induced Dysbiosis Predicts Mortality in an Animal Model of Clostridium difficile Infection

Antibiotic disruption of the intestinal microbiota favors colonization by Clostridium difficile. Using a charcoal-based adsorbent to decrease intestinal antibiotic concentrations, we studied the relationship between antibiotic concentrations in feces and the intensity of dysbiosis and quantified the...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Burdet, Charles, Sayah-Jeanne, Sakina, Nguyen, Thu Thuy, Hugon, Perrine, Sablier-Gallis, Frédérique, Saint-Lu, Nathalie, Corbel, Tanguy, Ferreira, Stéphanie, Pulse, Mark, Weiss, William, Andremont, Antoine, Mentré, France, de Gunzburg, Jean
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153837/
https://ncbi.nlm.nih.gov/pubmed/30061286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00925-18
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