Protection of Hamsters from Mortality by Reducing Fecal Moxifloxacin Concentration with DAV131A in a Model of Moxifloxacin-Induced Clostridium difficile Colitis

Lowering the gut exposure to antibiotics during treatments can prevent microbiota disruption. We evaluated the effects of an activated charcoal-based adsorbent, DAV131A, on the fecal free moxifloxacin concentration and mortality in a hamster model of moxifloxacin-induced Clostridium difficile infect...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Burdet, Charles, Sayah-Jeanne, Sakina, Nguyen, Thu Thuy, Miossec, Christine, Saint-Lu, Nathalie, Pulse, Mark, Weiss, William, Andremont, Antoine, Mentré, France, de Gunzburg, Jean
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610506/
https://ncbi.nlm.nih.gov/pubmed/28739791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00543-17
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