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Novel Mechanisms of Efflux-Mediated Levofloxacin Resistance and Reduced Amikacin Susceptibility in Stenotrophomonas maltophilia

Fluoroquinolone resistance in Stenotrophomonas maltophilia is multifactorial, but the most significant factor is overproduction of efflux pumps, particularly SmeDEF, following mutation. Here, we report that mutations in the glycosyl transferase gene smlt0622 in S. maltophilia K279a mutant K M6 cause...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Dulyayangkul, Punyawee, Calvopiña, Karina, Heesom, Kate J., Avison, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927820/
https://ncbi.nlm.nih.gov/pubmed/33139281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01284-20
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