Novel Mechanisms of Efflux-Mediated Levofloxacin Resistance and Reduced Amikacin Susceptibility in Stenotrophomonas maltophilia

Fluoroquinolone resistance in Stenotrophomonas maltophilia is multifactorial, but the most significant factor is overproduction of efflux pumps, particularly SmeDEF, following mutation. Here, we report that mutations in the glycosyl transferase gene smlt0622 in S. maltophilia K279a mutant K M6 cause...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Dulyayangkul, Punyawee, Calvopiña, Karina, Heesom, Kate J., Avison, Matthew B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927820/
https://ncbi.nlm.nih.gov/pubmed/33139281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01284-20
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