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Coordinate Hyperproduction of SmeZ and SmeJK Efflux Pumps Extends Drug Resistance in Stenotrophomonas maltophilia

A Stenotrophomonas maltophilia mutant that coordinately hyper-expresses three resistance nodulation division-type efflux pump genes, smeZ, smeJ, and smeK, has been identified. SmeZ is responsible for elevating aminoglycoside MICs; SmeJ and SmeK are jointly responsible for elevating tetracycline, min...

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Detalhes bibliográficos
Main Authors: Gould, Virginia C., Okazaki, Aki, Avison, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535947/
https://ncbi.nlm.nih.gov/pubmed/23147729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01020-12
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