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Complement C4A Regulates Autoreactive B Cells in Murine Lupus
Systemic lupus erythematosus (SLE) is a severe autoimmune disease mediated by pathogenic autoantibodies. While complement protein C4 is associated with SLE, its isoforms (C4A and C4B) are not equal in their impact. Despite being 99% homologous, genetic studies identified C4A as more protective than...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7927756/ https://ncbi.nlm.nih.gov/pubmed/33147456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108330 |
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