Intact Glucocorticoid Receptor Dimerization Is Deleterious in Trauma-Induced Impaired Fracture Healing

Following severe trauma, fracture healing is impaired because of overwhelming systemic and local inflammation. Glucocorticoids (GCs), acting via the glucocorticoid receptor (GR), influence fracture healing by modulating the trauma-induced immune response. GR dimerization-dependent gene regulation is...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Hachemi, Yasmine, Rapp, Anna E., Lee, Sooyeon, Dorn, Ann-Kristin, Krüger, Benjamin T., Kaiser, Kathrin, Ignatius, Anita, Tuckermann, Jan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927427/
https://ncbi.nlm.nih.gov/pubmed/33679723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.628287
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