Hypoxia and Hypoxia-Inducible Factor-1α Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion

Endoplasmic reticulum (ER) stress is shown to promote nucleus pulposus (NP) cell apoptosis and intervertebral disc degeneration. However, little is known about ER stress regulation by the hypoxic disc microenvironment and its contribution to extracellular matrix homeostasis. NP cells were cultured u...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Am J Pathol
Asıl Yazarlar: Novais, Emanuel J., Choi, Hyowon, Madhu, Vedavathi, Suyama, Kaori, Anjo, Sandra I., Manadas, Bruno, Shapiro, Irving M., Salgado, António J., Risbud, Makarand V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2021
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927276/
https://ncbi.nlm.nih.gov/pubmed/33307037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.11.012
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller