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Guanine nucleotide binding protein like-1 (GNL1) promotes cancer cell proliferation and survival through AKT/p21 (CIP1) signaling cascade

Human guanine nucleotide binding protein like 1 (GNL1) is an evolutionary conserved putative nucleolar GTPase belonging to the HSR1_MMR1 subfamily of GTPases. GNL1 was found to be highly up-regulated in various cancers. Here, we report for the first time that GNL1 inhibits apoptosis by modulating th...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Krishnan, Rehna, Murugiah, Mariappan, Lakshmi,, Naga Padma, Mahalingam, Sundarasamy
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927199/
https://ncbi.nlm.nih.gov/pubmed/33147101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0267
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