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Interplay between human nucleolar GNL1 and RPS20 is critical to modulate cell proliferation

Human Guanine nucleotide binding protein like 1 (GNL1) belongs to HSR1_MMR1 subfamily of nucleolar GTPases. Here, we report for the first time that GNL1 promotes cell cycle and proliferation by inducing hyperphosphorylation of retinoblastoma protein. Using yeast two-hybrid screening, Ribosomal prote...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Krishnan, Rehna, Boddapati, Neelima, Mahalingam, Sundarasamy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065441/
https://ncbi.nlm.nih.gov/pubmed/30061673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29802-y
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